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In this article, we will introduce the key points for selecting a model that will lead to the success of your PSC research.

 

Ideal features of a PSC model:

 

・Duct injury (intra- and extrahepatic)

・Ductular reaction

・Onion-like periductal fibrosis

・Portal inflammation

・Association with IBD

 

 

 

 

 

 

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But here’s the challenge:

There’s no single model that captures all these features

 

 

So, what’s the solution?

▶  Combine multiple PSC models for comprehensive evaluation.

 

 

How to choose the right combination?

▶  We’ve prepared a comparison table to help you select the most suitable models.

 

 

 

If you have any questions about the models or would like to discuss how you can use them in your research, please feel free to contact us.